Microsoft Azure today announced the new NDv6 GB300 VM series, delivering the industry's first supercomputing-scale production cluster of NVIDIA GB300 NVL72 systems, purpose-built for OpenAI's most demanding AI inference workloads.
This supercomputer-scale cluster features over 4,600 NVIDIA Blackwell Ultra GPUs connected via the NVIDIA Quantum-X800 InfiniBand networking platform. Microsoft's unique systems approach applied radical engineering to memory and networking to provide the massive scale of compute required to achieve high inference and training throughput for reasoning models and agentic AI systems.
Today's achievement is the result of years of deep partnership between NVIDIA and Microsoft purpose-building AI infrastructure for the world's most demanding AI workloads and to deliver infrastructure for the next frontier of AI. It marks another leadership moment, ensuring that leading-edge AI drives innovation in the United States.
Delivering the industry's first at-scale NVIDIA GB300 NVL72 production cluster for frontier AI is an achievement that goes beyond powerful silicon - it reflects Microsoft Azure and NVIDIA's shared commitment to optimize all parts of the modern AI data center, said Nidhi Chappell, corporate vice president of Microsoft Azure AI Infrastructure.
Our collaboration helps ensure customers like OpenAI can deploy next-generation infrastructure at unprecedented scale and speed.
Inside the Engine: The NVIDIA GB300 NVL72 At the heart of Azure's new NDv6 GB300 VM series is the liquid-cooled, rack-scale NVIDIA GB300 NVL72 system. Each rack is a powerhouse, integrating 72 NVIDIA Blackwell Ultra GPUs and 36 NVIDIA Grace CPUs into a single, cohesive unit to accelerate training and inference for massive AI models.
The system provides a staggering 37 terabytes of fast memory and 1.44 exaflops of FP4 Tensor Core performance per VM, creating a massive, unified memory space essential for reasoning models, agentic AI systems and complex multimodal generative AI.
NVIDIA Blackwell Ultra is supported by the full-stack NVIDIA AI platform, including collective communication libraries that tap into new formats like NVFP4 for breakthrough training performance, as well as compiler technologies like NVIDIA Dynamo for the highest inference performance in reasoning AI.
The NVIDIA Blackwell Ultra platform excels at both training and inference. In the recent MLPerf Inference v5.1 benchmarks, NVIDIA GB300 NVL72 systems delivered record-setting performance using NVFP4. Results included up to 5x higher throughput per GPU on the 671-billion-parameter DeepSeek-R1 reasoning model compared with the NVIDIA Hopper architecture, along with leadership performance on all newly introduced benchmarks like the Llama 3.1 405B model.
The Fabric of a Supercomputer: NVLink Switch and NVIDIA Quantum-X800 InfiniBand To connect over 4,600 Blackwell Ultra GPUs into a single, cohesive supercomputer, Microsoft Azure's cluster relies on a two-tiered NVIDIA networking architecture designed for both scale-up performance within the rack and scale-out performance across the entire cluster.
Within each GB300 NVL72 rack, the fifth-generation NVIDIA NVLink Switch fabric provides 130 TB/s of direct, all-to-all bandwidth between the 72 Blackwell Ultra GPUs. This transforms the entire rack into a single, unified accelerator with a shared memory pool - a critical design for massive, memory-intensive models.
To scale beyond the rack, the cluster uses the NVIDIA Quantum-X800 InfiniBand platform, purpose-built for trillion-parameter-scale AI. Featuring NVIDIA ConnectX-8 SuperNICs and Quantum-X800 switches, NVIDIA Quantum-X800 provides 800 Gb/s of bandwidth per GPU, ensuring seamless communication across all 4,608 GPUs.
Microsoft Azure's cluster also uses NVIDIA Quantum-X800's advanced adaptive routing, telemetry-based congestion control and performance isolation capabilities, as well as NVIDIA Scalable Hierarchical Aggregation and Reduction Protocol (SHARP) v4, which accelerates operations to significantly boost the efficiency of large-scale training and inference.
Driving the Future of AI Delivering the world's first production NVIDIA GB300 NVL72 cluster at this scale required a reimagination of every layer of Microsoft's data center - from custom liquid cooling and power distribution to a reengineered software stack for orchestration and storage.
This latest milestone marks a big step forward in building the infrastructure that will unlock the future of AI. As Azure scales to its goal of deploying hundreds of thousands of NVIDIA Blackwell Ultra GPUs, even more innovations are poised to emerge from customers like OpenAI.
Learn more about this announcement on the Microsoft Azure blog.
Most recent headlines
11/12/2025
Dalet, a leading provider of cloud-native, end-to-end media workflow solutions, ...
28/11/2025
Nadia Fall attends the 2025 Sundance Film Festival premiere of Brides at the Egyptian Theatre on January 24, 2025, in Park City, Utah. (Photo by Donyale West/...
28/11/2025
It's easy to ignore those little red update available badges. But when it ...
28/11/2025
WASHINGTON Federal Communications Commission has released a tentative agenda for the December Open Commission Meeting scheduled for Thursday, December 18, 2025 ...
28/11/2025
The Professional Fighters League is looking to super-serve fans of mixed martial...
28/11/2025
Fubo has released in beta on select Roku devices a new feature that lets users display up to four simultaneous streams at once....
28/11/2025
The WNBA playoffs and Week 4 of the NFL regular season highlight the list of live sports events airing on television this weekend....
28/11/2025
The 32nd class of honorees to the B+C Hall of Fame took to the stage at New York's Ziegfeld Ballroom on September 26 for a gala induction event. Click below...
28/11/2025
We hold in our hands the very last Next Text for Next TV, the weekly back-and-fo...
28/11/2025
DirecTV said it made a deal with EchoStar to buy EchoStar's video businesses, including satellite-TV provider Dish TV and virtual MVPD Sling TV, for $1 plus...
28/11/2025
The Broadcasting+Cable Hall of Fame, the premier industry event paying tribute to the influencers, innovators and shining lights of broadcast, cable and streami...
28/11/2025
Friday 28 November 2025
Sky Sports x Slawn drop limited-edition football jersey...
28/11/2025
Rohde & Schwarz shows resilience in a challenging environment, revenue exceeds t...
28/11/2025
Unwrapped: The Toy Show Appeal - airing this Sunday on RT One and RT Player- s...
27/11/2025
LONDON Vizrt has added several AI-driven advanced features offering improved speed, intelligence and accuracy in the newest version of its media asset managemen...
27/11/2025
Prime Video has launched AI-powered video season recaps in a beta version for select English-language Prime Original series in the U.S., a move Amazon is callin...
27/11/2025
Back to All News
Netflix's Raat Akeli Hai: The Bansal Murders Marks a Grand...
27/11/2025
27 Nov 2025
GSMA brings M360 Eurasia 2026 to Samarkand in partnership with VEON...
27/11/2025
Tahar Rahim and Izuka Hoyle star in the gripping six-part Sky Original from Acad...
27/11/2025
Thursday 27 November 2025
Sky Arts Reveals the Nation's Greatest Basslines - and Queen Reign Supreme
The UK's most iconic basslines have been revealed...
27/11/2025
Back to All News
Stranger Things 5': Prepare for One Last Adventure With O...
27/11/2025
The media industry has a paradox at its core. It's an industry built on light, color and imagination, yet behind the scenes, it's powered by one of the ...
27/11/2025
Rating reflects rating progress across areas including policies, diversity & inclusion, health & safety and Net Zero leadership
Winchester, UK, 27 November 202...
27/11/2025
What are the industry standards for Retail Media? Kathryn explains that certification is based on the IAB Europe Retail Media Measurement Standards and the IAB ...
27/11/2025
World champion boxer and Irish sporting icon Katie Taylor will be in studio this...
27/11/2025
Roblox, one of the world's most popular online gaming platforms for primary ...
27/11/2025
Black Friday is leveling up. Get ready to score one of the biggest deals of the season - 50% off the first three months of a new GeForce NOW Ultimate membership...
26/11/2025
SVG Sit-Down: Prime Video EP Mike Muriano Previews Massive Black Friday Slate Fe...
26/11/2025
A cinematic snow sculpture at the 1995 Sundance Film Festival. Photo by Randall Michelson...
26/11/2025
Book podcasts are booming. On Spotify, you'll find everything from celebrity book clubs to deep dives with bestselling authors. And in markets where audiobo...
26/11/2025
Mumbai, November 24, 2025: In a first-of-its-kind initiative, JioStar, in collab...
26/11/2025
LONDON Factual content producer ITN Productions has launched a new low-latency IP gallery for news bulletins....
26/11/2025
MIAMI TelevisaUnivision said it struck a new multiyear distribution agreement with YouTube TV that includes distribution of TelevisaUnivision's U.S. network...
26/11/2025
OpenDrives, Inc., a leader in software-defined data storage and data services, today announced the launch of the Atlas Corporate Creative Solution. This new Atl...
26/11/2025
Disguise, the industry-leading company powering the world's biggest live performances, is partnering with pioneering LED wall manufacturer DVS to give atten...
26/11/2025
HighField AI, the pioneer in agentic and multimodal automation for broadcast and media production, today announced the expansion of its global channel partner n...
26/11/2025
As high-stakes Premier League fixtures approach and additional premium content launches, with MONO positioning themselves to dominate Thailand's sports stre...
26/11/2025
Hosting a wide variety of events from high-intensity NHL games to complex live music concerts and major entertainment productions, Montreal's 21,000 capacit...
26/11/2025
Vizrt, the leader in live production technology revolutionizing viewer engagement and experience, releases AI-driven advances focusing on speed, intelligence, a...
26/11/2025
ITN Productions, an award-winning factual content producer, today launched a new low-latency IP gallery for news bulletins. Responsible for delivering a leading...
26/11/2025
Ikegami reports ongoing advances throughout 2025 in developing and delivering coordinated television production solutions that maximize quality, versatility and...
26/11/2025
Following the Nov. 21 blackout of NBCUniversal channels on Fubo, the two sides have traded barbs about their inability to reach a new carriage deal....
26/11/2025
LONDON As TV sports rights become increasingly important for both broadcasters and streamers, Ampere Analysis predicts global investment in the genre will surpa...
26/11/2025
LOS ANGELES Vubiquity said it has achieved the Amazon Web Services (AWS) Media & Entertainment Competency as part of the AWS Partner Network (APN). This designa...
26/11/2025
WASHINGTON The Federal Communications Commission's Enforcement Bureau said it has entered into a consent decree with Comcast calling for the cable company t...
26/11/2025
Berklee Named to the Hollywood Reporters Top Music Schools List The publication highlights the college's screen scoring program, industry partnerships, and ...
26/11/2025
Back to All News
Animated Series Love Through a Prism' Casts New Light on ...
26/11/2025
Back to All News
NALIP Unveils Fifth Cohort of Director Incubator
Social Impact
26 November 2025
United States
Link copied to clipboard
The National Assoc...
26/11/2025
YouView Achieves Greenly Gold Certification for SustainabilityNov 26, 2025
YouView is proud to announce a Gold Certification award from Greenly for our perform...
Microsoft Azure today announced the new NDv6 GB300 VM series, delivering the industry's first supercomputing-scale production cluster of NVIDIA GB300 NVL72 systems, purpose-built for OpenAI's most demanding AI inference workloads.
