In the global race to tame the spread of COVID-19, scientific researchers and pharmaceutical companies first must understand the virus's protein structure.
Doing so requires building detailed 3D models of protein molecules, which until recently has been an intensely time-consuming task. Structura Biotechnology's groundbreaking software is helping speed things along.
The GPU-powered machine learning algorithms underlying Structura's software power the image processing stage of a technology called cryo-electron microscopy, or cryo-EM, a revolutionary breakthrough in biochemistry that was the subject of the 2017 Nobel Prize in chemistry.
Cryo-EM enables powerful electron microscopes to capture detailed images of biomolecules in their near-native states. These images can then be used to reconstruct a 3D model of the biomolecules.
With cryo-EM providing valuable 2D image data, Structura's AI-infused software, called cryoSPARC, can quickly analyze the resulting microscopy data to solve the 3D atomic structures of the embedded protein molecules. That, in turn, allows researchers to more rapidly gauge how effective drugs will be in binding to those molecules, significantly speeding up the process of drug discovery.
Hundreds of labs around the world already use the three-year-old Toronto-based company's software, with a significant, but not surprising, surge during 2020. In fact, CEO Ali Punjani states that Structura's software has been used by scientists to visualize COVID-19 proteins in multiple publications.
Our software helps scientists to understand what their proteins look like and how their proposed therapeutics may bind, Punjani said. The more they can see about the structure of the target, the easier it becomes to design or identify a molecule that locks onto that structure and stops it.
An Intriguing Test Case The idea for Structura came from a conversation Punjani overheard, during his undergraduate work at the University of Toronto, about trying to solve protein structures using microscopic images. He thought the topic would make an intriguing test case for his developing interest in machine learning research.
Punjani formed his team in 2017, and Structura started building its software, backed by large-scale inference and computer vision algorithms that help to recover a 3D model from 2D image data. The key, he said, is to collect and analyze - with increasing accuracy - a sufficient amount of microscopic data to enable high-quality 3D reconstructions.
It's a highly scientific domain with zero tolerance for error, Punjani said. Getting it wrong can be a huge waste of time and money.
Structura's software is deployed on premises, typically on customers' hardware, which must be up to the task of processing real-time 3D microscope data. Punjani said labs often run this work on NVIDIA Quadro RTX 6000 GPUs, or something similar, while many larger pharmaceutical companies have invested in clusters of NVIDIA V100 Tensor Core GPUs accompanied by a variety of NVIDIA graphics cards.
Structura does all of its model training and software development on machines running multi-GPU nodes of V100 GPUs. Punjani said his team writes all of its GPU kernels from scratch because of the particular and exotic nature of the problem. The code that runs on Structura's GPUs is written in CUDA, while cuDNN is used for some high-end computing tasks.
Right Software at the Right Time Given the value of Structura's innovations, and the importance of cryo-EM, Punjani isn't holding back on his ambitions for the company, which recently joined NVIDIA Inception, an accelerator program designed to nurture startups revolutionizing industries with advancements in AI and data sciences.
Punjani says that any research related to living things can now make use of the information from 3D protein structures that cryo-EM offers and, as a result, there's a lot of industry attention focused on the kind of work Structura's software enables.
What we're building right now is a fundamental building block for cryo-EM to better enable structure-based drug discovery, he said. Cryo-EM is set to become ubiquitous throughout all biological research.
Stay up to date with the latest healthcare news from NVIDIA.
Most recent headlines
05/01/2027
Worlds first 802.15.4ab-UWB chip verified by Calterah and Rohde & Schwarz to be ...
04/08/2026
Dalet, a leading technology and service provider for media-rich organizations, t...
04/07/2026
April 7 2026, 19:00 (PDT) Detective Conan: Fallen Angel of the Highway Opens in...
01/06/2026
January 6 2026, 05:30 (PST) Dolby Sets the New Standard for Premium Entertainment at CES 2026
Throughout the week, Dolby brings to life the latest innovatio...
18/05/2026
Despite a bumpy start to the year, the provider of event-production support and ...
18/05/2026
Daktronics has partnered with the University of North Carolina to manufacture and install 11 LED displays totaling more than 10,000 square feet and more than 14...
18/05/2026
CBS LA has announced a multi-year partnership with the Los Angeles Rams, covering exclusive local broadcasts of Rams preseason games, weekly year-round programm...
18/05/2026
Skyline Communications has announced an integration between its DataMiner xOps p...
18/05/2026
eCLUTCH, the hybrid esports platform powered by iKOMG, has announced an expansion of its distribution across Europe, MENA, Africa, and Asia, along with new cont...
18/05/2026
Behind The Mic provides a roundup of recent news regarding on-air talent, includ...
18/05/2026
With 22 games this season, the production team looks forward to tweaking and enhancing the coverage
After 8,660 days off the air, the WNBA returned to NBC yest...
18/05/2026
(L-R) Midori Francis and Natalie Erika James attend the Saccharine premiere during the 2026 Sundance Film Festival at The Ray Theatre on January 22, 2026, in ...
18/05/2026
Last night, the Spotify Podcast Awards in Mexico returned to the country's capital. Now in its second year, the evening honors creators whose voices are hel...
18/05/2026
ZEN-Core synth goes mobile
Roland's powerful ZEN-Core software synthesizer has just been introduced to the iPad, offering a convenient entry point into ...
18/05/2026
Versatile new limiter plug-in announced
Based in Sheffield, UK, fedDSP offer a range of plug-ins that span the music production, live sound and high-end med...
18/05/2026
A new use for convolution?
Viiri Audio's debut plug-in aims to do something a little different with convolution processing, allowing users to adjust all...
18/05/2026
Delta Goodrem shines for SBS as more than 3.27 million Australians tune in for E...
18/05/2026
The Australian Defence Force uses L3Harris T4 and T7 robots for explosive ordnan...
18/05/2026
Continued investment across Europe and Germany is expanding local teams and improving access to stock, regional expertise, and specialist broadcast support.
CV...
18/05/2026
18 May 2026
Dubai and New York, May 18, 2026 - VEON Ltd. (NASDAQ: VEON), a glob...
18/05/2026
Monday 18 May 2026
Sky News offers ad-free podcasts and bonus episodes for just...
18/05/2026
Comscore March 2026 Consumer AI Chatbot Usage Rankings Show Claude Gaining Share OpenAI's ChatGPT maintains lead while Anthropic's Claude continues to c...
17/05/2026
Delta Goodrem's Eurovision Eclipse marks end of a stellar run
17 May, 2026
Media releases
Bulgaria wins Eurovision 2026
Relive every spellbinding mome...
17/05/2026
Back to All News
Oasis Premieres on Netflix June 19
Entertainment
17 May 2026
GlobalSpain
Link copied to clipboard
Summer, sunshine, the beach, parties. T...
16/05/2026
Helps to deliver a clean, balanced midrange
Developed alongside Newfangled Audio, the latest plug-in in Eventide's software collection has been designed...
16/05/2026
Brings onboard stem rendering to RANE System One
Engine DJ have just released Engine DJ 5.0, a free update for their Engine DJ OS embedded hardware and Engi...
16/05/2026
Boris FX Continuum Pairs AI Precision and Advanced Creative Controls
Jessie Electa Petrov May 16, 2026
0 Comments
The 2026.5 release adds automatic de...
16/05/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
16/05/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
16/05/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
16/05/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
15/05/2026
Seattle Sounders FC and Seattle Reign FC, in partnership with RAVE Foundation an...
15/05/2026
Dan Brumm has served as sound designer on Bluey, the Australian children's t...
15/05/2026
The Professional Audio Manufacturers Alliance (PAMA) and Shure Incorporated are accepting applications for the 6th annual Mark Brunner Professional Audio Schola...
15/05/2026
Netflix has announced an expanded NFL schedule for 2026 and beyond under a four-year partnership extension with the NFL through the 2029-30 season. Each season,...
15/05/2026
Ateme is supporting TVRI (Televisi Republik Indonesia) with a contribution and d...
15/05/2026
Concacaf has announced the launch of a new website and mobile app built on Deltatre's FORGE platform. Concacaf.com and the mobile app, available on iOS and ...
15/05/2026
Eutelsat has announced the launch of QBC Business Economic Channel by Qatar Media Corporation, broadcasting in 4K/UHD via Eutelsat's 7/8 West video neighbo...
15/05/2026
Major League Soccer has announced four original content series timed to the 2026...
15/05/2026
The Alliance for IP Media Solutions (AIMS) has announced it will exhibit and present at InfoComm 2026, taking place June 13-19 at the Las Vegas Convention Cente...
15/05/2026
InfoComm 2026 will take place June 13-19 (exhibits June 17-19) at the Las Vegas Convention Center. The show will include sessions and exhibits covering broadcas...
15/05/2026
Tracy McGrady's Ones Basketball League (OBL) and FuboTV Inc. have announced ...
15/05/2026
Disguise has partnered with Creative Technology (CT) to deliver visual playback ...
15/05/2026
Sony Electronics has announced two new products for professional imaging: the Alpha 7R VI full-frame mirrorless camera and the FE 100-400mm F4.5 GM OSS super-te...
15/05/2026
In-venue and creative video staffers at the professional and collegiate level ha...
15/05/2026
Ratings Roundup is a rundown of recent rating news and is derived from press rel...
15/05/2026
For sports organizations, the most valuable assets are often the most sensitive:...
15/05/2026
The NFL's broadcast partners released their 2026 regular season schedules ye...
15/05/2026
Besides drawing on experience with boxing, the production integrates specialty c...
In the global race to tame the spread of COVID-19, scientific researchers and pharmaceutical companies first must understand the virus's protein structure.
