At least 1 in 3 people infected with COVID-19 never develop symptoms, according to new analysis Findings suggest COVID-19 testing should be expanded to those without symptoms who may be unknowingly spreading the virus.
January 22, 2021
LA JOLLA, CA A new data analysis including more than 1.8 million people confirms that asymptomatic infections of the SARS-CoV-2 virus are a major portion of COVID-19's global footprint, representing at least a third of cases.
The findings, published today in Annals of Internal Medicine, build on the authors' prior review of more limited data sets in June 2020, which also found that a significant proportion of SARS-CoV-2 infections did not produce symptoms.
In the new report, Scripps Research's Eric Topol, MD, and Daniel Oran once again dig into the data, this time reviewing a much larger set of 61 studies and reports from around the world including two massive serosurveys in England and Spain that tested the presence of SARS-CoV-2 antibodies in hundreds of thousands of people. In both of those studies, about one-third of the individuals were shown to have had the virus but never experienced symptoms.
The biggest implication of this is that we need to test far more widely and frequently, and not confined to people with symptoms, says Topol, founder and director of the Scripps Research Translational Institute and professor of Molecular Medicine at Scripps Research. We need to urgently get rapid home antigen tests to every household for daily use.
Inexpensive, at-home testing would also help identify those who are presymptomatic, which means they have not yet developed symptoms. About half of all new infections are believed to be caused by people who are either presymptomatic or asymptomatic.
Another implication of our review is that we need to figure out how effective vaccines are in preventing asymptomatic infection, says Oran, a member of the digital medicine group at Scripps Research Translational Institute. Early data are encouraging, but we still have a lot more to learn.
The authors note that it was just about one year ago on January 24, 2020 that the first asymptomatic case of COVID-19 was documented, but largely ignored.
Now we know with certainty that asymptomatic infection is a notable feature of SARS-CoV-2 , Topol says. It's time that we translate this knowledge into smarter testing practices that will help to bring COVID-19 under control.
Video: Eric Topol and Danny Oran discuss asymptomatic COVID-19
COVID-19 Translational Medicine Topol, Eric
Most recent headlines
05/01/2027
Worlds first 802.15.4ab-UWB chip verified by Calterah and Rohde & Schwarz to be ...
04/08/2026
Dalet, a leading technology and service provider for media-rich organizations, t...
04/07/2026
April 7 2026, 19:00 (PDT) Detective Conan: Fallen Angel of the Highway Opens in...
01/06/2026
January 6 2026, 05:30 (PST) Dolby Sets the New Standard for Premium Entertainment at CES 2026
Throughout the week, Dolby brings to life the latest innovatio...
02/05/2026
Dalet, a leading technology and service provider for media-rich organizations, t...
01/05/2026
January 5 2026, 18:30 (PST) NBCUniversal's Peacock to Be First Streamer to ...
21/04/2026
Cloud-based production isnt going anywhere, and BitFire is doubling down by prov...
21/04/2026
The topic of artificial intelligence has a stranglehold on the sports-video-prod...
21/04/2026
5G is still a hot topic in live event production, and this workflow continues to...
21/04/2026
At the 2026 NAB Show, Ed McGivern, GM and President of Appear US, discusses the ...
21/04/2026
Studio Network Solutions (SNS) has announced an on-premise AI suite designed for...
21/04/2026
Suite Studios has integrated its file-streaming technology into the newly announced Frame.io Drive, a desktop application from Adobe company Frame.io. The colla...
21/04/2026
Net Insight has integrated InSync Technology's FrameFormer into the Nimbra E...
21/04/2026
Fox Sports has selected Appear as a technology partner to support the next phase...
21/04/2026
Diversified has appointed Tyler Affolter as Chief Revenue Officer (CRO) to lead the company's commercial organisation. The appointment follows the firm'...
21/04/2026
Layercake has formalised the integration of Bitmovin's video streaming infra...
21/04/2026
The International Judo Federation (IJF) has extended its distribution partnershi...
21/04/2026
Glookast has launched the Cinnafilm Tachyon plugin for its Media Producer and Me...
21/04/2026
Eutelsat has entered into an agreement with Cadena Tres, a division of Grupo Ima...
21/04/2026
Dolby Laboratories and TV Azteca have partnered to introduce Dolby Atmos immersive audio to free-to-air television broadcasts. The implementation utilises the A...
21/04/2026
FOX Entertainment partnered with Verizon to overcome significant production hurd...
21/04/2026
Osprey Video has announced its technology showcase for the NAB Show 2026, highli...
21/04/2026
Riedel Communications (Booth C4908) introduced a range of new solutions at NAB S...
21/04/2026
The NAB Show is in full swing, and the SVG and SVG Europe editorial teams are chasing down the hottest stories from all over the Las Vegas Convention Center. He...
21/04/2026
Blackmagic Design has announced the URSA Cine Immersive 100G, an immersive cinem...
21/04/2026
Clark Wire & Cable is continuing its evolution from cable supplier to full-scale solutions partner for broadcast and live production. At the 2026 NAB Show, we s...
21/04/2026
Rashad Frett attends the 2025 Sundance Film Festival premiere of Ricky at Eccles Theatre on January 24, 2025, in Park City, UT. (Photo by George Pimentel/Shut...
21/04/2026
Five years ago, Spotify arrived in Pakistan, opening a new chapter in the country's music scene. Since then, local listeners have explored across genres, ge...
21/04/2026
Since its launch in 2020, RADAR has been our program for spotlighting emerging artists around the world. This year marks the sixth edition of RADAR Spain, our o...
21/04/2026
Offers compact wireless solution for pedalboards
Taiwanese audio brand Cloudvocal have announced the availability of a new pedalboard-friendly wireless syst...
21/04/2026
Latest hybrid sampling/synthesis instrument arrives
Arturia's Augmented series offerings rely on a mixture of sampling and synthesis, allowing users to ...
21/04/2026
Rohde & Schwarz to host Power Electronics Online Conference From Design to Vali...
21/04/2026
MAS and Lockheed Martin partner to establish an F-35 depot in Canada, enabling in-country sustainment and creating high-skilled aerospace jobs....
21/04/2026
Advertising strategies shift as competition grows for a large, active and qualit...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
21/04/2026
Layercake Deepens Bitmovin Integration to Power End-to-End Media Orchestration w...
21/04/2026
Cobalt Digital Announces Launch of blueCORE at NAB Show 2026: Compact Powerhouse...
21/04/2026
On-Premise AI Suite from Studio Network Solutions Debuts at NAB Show 2026
Melanie Ciotti April 21, 2026
0 Comments
Unlimited processing, no cloud depe...
21/04/2026
London, 21 April 2026 IBC today announced the appointment of Tim Banham as its first Chief Commercial Officer (CCO), a newly created role that reflects the or...
21/04/2026
Motion Design Tools - April 2026
Roland Kahlenberg April 21, 2026
0 Comments
Within 2 days, Maxon and Canva announced pro-level motion design apps - A...
21/04/2026
Chaos and Zero Density to Showcase Real-Time Ray Tracing for Virtual Studios and...
21/04/2026
Share
Copy link
Facebook
X
Linkedin
Bluesky
Email...
At least 1 in 3 people infected with COVID-19 never develop symptoms, according to new analysis Findings suggest COVID-19 testing should be expanded to those without symptoms who may be unknowingly spreading the virus.
