Sony Digital Rapids Pixel Power calrec Sony

Mobile health devices diagnose hidden heart condition in at-risk populations

11/07/2018

Mobile health devices diagnose hidden heart condition in at-risk populations LA JOLLA, CA July 10, 2018 - Wearable mobile health devices improved the rate of diagnosis of a dangerous and often hidden heart condition called atrial fibrillation (AFib), according to a first of its kind, home-based clinical study conducted in part by researchers at the Scripps Translational Science Institute (STSI).

By catching AFib, which can increase the risk of stroke fivefold, in people who are at risk but might have gone undiagnosed, the mobile health (mHealth) devices resulted in more people receiving critical preventive therapies, the study found.

Our study shows an almost threefold improvement in the rate of diagnosis of AFib in the those actively monitored compared to usual care, says Steven Steinhubl, MD, director of digital medicine at STSI and an associate professor at The Scripps Research Institute (TSRI). Timely diagnosis of AFib more effectively can enable the initiation of effective therapies and help reduce strokes and death.

Findings from the mHealth Screening To Prevent Strokes (mSToPS) study were published today in the Journal of the American Medical Association.

A need for better screening

As many as six million Americans live with AFib, an irregular heartbeat (arrhythmia) that beyond its associated stroke risk also doubles the risk of death. Fortunately, effective therapies can help substantially reduce the risk of stroke in individuals diagnosed with AFib. However, approximately a third of individuals with the disorder are asymptomatic, and the lack of effective screening prevents or delays diagnosis and treatment.

Recent advances in digital medicine technologies present opportunities for both innovative screening strategies, as well as more inclusive and participant-centric approaches to clinical research. Novel mobile health (mHealth) devices can provide a means of monitoring AFib more effectively and continuously without interfering with routine activities.

The mSToPS study sought to compare outcomes of intermittent screening for AFib during regular visits to a primary care physician with continuous, single-lead electrocardiogram (ECG) monitoring using a patch sensor. The primary objective was to determine whether monitoring with wearable sensor technology can identify people with asymptomatic AFib more efficiently than routine care.

Re-imagining clinical research

STSI researchers teamed with Aetna's Healthagen Outcomes unit and Janssen Pharmaceuticals, Inc., to conduct the study using the FDA approved wireless iRhythm Zio XT patch for ECG screening. Aetna's data and analytics made the innovative study design possible.

The study population consisted of members of the Aetna fully insured Commercial and Medicare health plans. Using Aetna's data sets, eligible members were identified based on clinical characteristics associated with a possible increased incidence of AFib. They were invited to participate in the study through a nationwide email outreach campaign that then enabled interested participants to enroll through a web-based digital consent process.

The digital outreach and enrollment, and the home-based approach meant that anyone who met the inclusion criteria could participate in the study, regardless of their geographical location.

All of the study data was participant-generated, with individuals self-applying the wearable sensor they received in the mail and returning it to iRhythm for analysis once they had worn the patch for up to two weeks. The generated data was also returned to the monitored participants and, with their approval, to their physicians.

A total of 5,214 individuals were included in the one-year analysis, with a third being assigned to the monitored cohort and the rest being observational controls. AFib was newly diagnosed in 6.3 percent of the monitored participants and in 2.4 percent of the controls.

According to Steinhubl, this is the first study to describe the early term clinical consequences of active ECG screening. By reviewing claims data, the researchers observed that active monitoring was associated with increased initiation of anticoagulant and antiarrhythmic therapies.

This study demonstrates the utility of a digital approach not only to diagnosing asymptomatic AFib, but to the clinical research field as a whole, says Steinhubl. We hope that it will set a precedent for future real-world, participant-centric clinical trials that leverage the power of digital medicine technologies.

STSI's founder and director Eric Topol, MD, also a TSRI professor, deems the use of digital sensors as vital to the future of medicine and clinical research. For clinical research to change practice it needs to be more participant focused and reflect the real world of those participants, by taking advantage of digital tools and infrastructure that is possible as never before, says Topol.

Additional authors of the study, Effect of a Home-Based Wearable Continuous ECG Monitoring Patch on Detection of Undiagnosed Atrial Fibrillation were Jill Waalen, Lauren Ariniello and Katie Baca-Motes of the Scripps Translational Science Institute; Alison Edwards and Rajesh Mehta of Healthagen Outcomes; and Chureen Carter, Elise Felicione and Troy Sarich of Janssen Scientific Affairs.

The research was supported by a research grant from Janssen Pharmaceuticals. Additional support was provided by a National Institutes of Health's National Center for Advancing Translational Sciences grant (UL1TROO1114) and a grant from Qualcomm Foundation.

About Scripps Research

Scripps Research is one of the worlds preeminent independent, not-for-profit organizations focusing on research in the biomedical sciences. Scripps Research is internationally recognized for its contributions to science and health, including its role in laying the foundation f
LINK: http://www.scripps.edu/news/press/2018/20180709-heart-health-afib.html...
See more stories from scripps

Europe Stories

17/11/2018

Technicolor's Maxine Gervais and The Mill's Adam Scott Win 2018 HPA Awards for Outstanding Color Grading

OUTSTANDING COLOR GRADING - FEATURE FILM WINNER Alpha Technicolor Maxine Ge...

17/11/2018

Who Will Win the Latin Grammy Awards? Here's What Our Streaming Data Says

Honoring the biggest stars in Latin music, the 19th Annual Latin Grammy Awards on November 15 are just around the corner, and the lucky winners are anyone's...

17/11/2018

Herrick Goldman Explores Elation ZCL, Artiste on Mamma Mia

Herrick Goldman Explores Elation ZCL , Artiste on Mamma Mia posted: 17/11/2018 Leading theatre lighting designer Herrick Goldman recently lit a Cape Re...

17/11/2018

DPA Microphones Deliver Clear and Consistent Sound on Mission: Impossible- Fallout

DPA Microphones Deliver Clear and Consistent Sound on Mission: Impossible - Fall...

17/11/2018

RDECaster Pro is an all-in-one studio for podcasters

Features 8 channels, Bluetooth, USB and phone inputs, SFX pads, SD recording and more! Hardware > Recording System Production Podcasting continues to be one...

17/11/2018

Akai's MPC 2.3 update adds three new synths and autosampling

Synths from AIR added as well as crossfade looping and an arpeggiator Hardware > Sampler, Sequencer Software > Virtual Instrument Akai really upped their MP...

17/11/2018

dB Makes Top Companies Listing

November 2018 dB Broadcast has been listed once again in the honour role of top Cambridgeshire companies. The annual report, compiled by Grant Thornton and Mi...

17/11/2018

Opportunities at dB Broadcast in 2019

November 2018 dB continues to experience a period of impressive growth with a line-up of top name clients and cutting edge projects in broadcast system install...

17/11/2018

I'm A Celebrity...Get Me Out Of Here! trailer

Published: Fri 16 Nov 2018 Video of IACGMOOH18 Sneak peek at Im A Celebrity...Get Me Out Of Here! trailer airing on ITV tonight This is the first look at De...

17/11/2018

Arvato Systems building AWS expertise

Arvato Systems increases Amazon Web Services skill-set 50 AWS certifications awarded G tersloh - Just a year after launching the AWS Business Group', Arv...

17/11/2018

50 Ways to Make it Better

50 Ways to Make it Better...

17/11/2018

IPI World Congress heads to Geneva in partnership with EBU

IPI World Congress heads to Geneva in partnership with EBU...

16/11/2018

Data and Analytics: Advice from European TV Operators

16 November 2018 Data and Analytics: Advice from European TV Operators Share Data projects are complicated, hard work and expensive. Most TV providers ar...

16/11/2018

First in Finland: Nokia signs the UN Standards of Conduct for Business to pledge support for LGBTI rights worldwide

Press Release Nokia is the first company in Finland to sign the United Nations...

16/11/2018

Segovia welcomes a new 5G use case

Use case is applicable to Industry 4.0 with remote monitoring of assembly work Demonstrates need for low-latency 5G to support the offer of certain services F...

16/11/2018

EE and Virgin Media fined for overcharging customers

EE and Virgin Media fined for overcharging customers Add to Your Pages 16 November 2018 Ofcom fines EE 6.3m and Virgin Media 7m for breaking consume...

16/11/2018

SGL Carbon receives major order for heat exchangers in China

Order value in the low single-digit million euro range Large package including corrosion-resistant heat exchangers, bellows and piping SGL Carbon received a ...

16/11/2018

2018-11-15

The latest update to Final Cut Pro X, available today on the Mac App Store, introduces workflow extensions that enable professional video editors to use third-p...

16/11/2018

BBC Studioworks pulls out all the stops for Children in Need

Sixth annual show to be broadcast tonight Author: Ann-Marie CorvinPublish date: Nov 16, 2018 BBC's Children in Need Appeal show is to be broadcast this ...

16/11/2018

240 jobs under threat as...

Jan De Witte, Chief Executive Officer of Barco Barco has announced a restructuring plan to align the organisation with changing market demands and growth oppor...

16/11/2018

HK Audio appoints Sisme as its exclusive...

L-R: Christian Jordan (HK Audio), Claudio Bugari (Sisme), Antonio Sciarrillo (Sisme), Nils Stamer (HK Audio) HK Audio has increased its presence in Italy by ap...

16/11/2018

Crestron EMEA opens Milan office

Crestron EMEA has opened a new office in Milan. This latest location for Crestron, which includes offices and an experience centre, opened November 15, and is s...

16/11/2018

Samsung kill Soundcamp Android music making app

Backup your data by December 28... Software > App Android users have long been at a bit of a disadvantage when it comes to mobile music making compared to th...

16/11/2018

Barco to highlight advances in remote reading, streamlined compliance and analytics at RSNA 2018

Barco to highlight advances in remote reading, streamlined compliance and analyt...

16/11/2018

Work Microwave and University of Munich carry out DVB-S2X ACM test

Pair join forces on field-test Author: Ann-Marie CorvinPublish date: Nov 16, 2018 Proper planning and management of well-designed ground equipment make it p...

16/11/2018

Farm Bristol moves to very big house in the country

Move will help The Farm deal with "growing demand" for post work in the region Author: Ann-Marie CorvinPublish date: Nov 16, 2018 British based facility gro...

16/11/2018

Dejero honoured with Technology Emmy

Ontario-based company has been awarded for its work in Pioneering Reliable Transmission Method for Live Contribution and Distribution TV Links' Author: A...

16/11/2018

FOX Sports' College Football Pre-Game Show Relies on Clear-Com for Flexible Wireless Communications

FOX Sports' College Football Pre-Game Show Relies on Clear-Com for Flexible ...

16/11/2018

Cinema 4D at Us By Night 2018

From November 22-24, Antwerp will again be the place to be for thousands of artists from around the world. The Us By Night festival offers an inspiring, high-en...

16/11/2018

MTN, Ericsson and Netstar record 5G first for South Africa

The field deployment in Midrand, situated between Johannesburg and Tshwane (Pretoria), is part of Ericsson's continuing efforts to deliver end-to-end 5G cap...

16/11/2018

15 Nov 2018

And the winner is Posted on 15 Nov 2018 *Drum roll* We wont keep you in suspense! ICG is delighted to announce we came away winners of Prolific Norths Northe...

16/11/2018

Nokia, AT&T and Jaunt to show football fans how 5G can help enable the future of mobile content and immersive experiences

Press Release Live demonstration showcased at Atlanta Falcons vs. Dallas Cowboy...

16/11/2018

Digigram as Auvitran's exclusive distributor in the APAC region

Digigram Asia Pte Ltd announces its appointment as exclusive authorized Distributor for Auvitran on APAC region. Singapore November, 13th 2018 Digigram Asi...

16/11/2018

Media Alert: Adobe Named a Leader in Web Content Management Systems by Independent Research Firm

SAN JOSE, Calif. - Nov. 15, 2018 - Adobe (Nasdaq:ADBE) today announced it was re...

16/11/2018

tvebiomovies voting selects two youth reporters to attend climate talks

With the votes in and counted for the Global Youth Video Competition on Climate Change, part of tvebiomovies, two young film makers have been selected as the wi...

16/11/2018

GSMA Welcomes Germany's 5G Spectrum Award, but Cautions Against Unnecessary Conditions

License Conditions in Upcoming Award Could Hinder 5G's Promise for Consumers...

16/11/2018

Akamai Identified as a Powerhouse in the Network Security Space in Report by Independent Research Firm

Akamai Identified as a Powerhouse in the Network Security Space in Report by Ind...

15/11/2018

Mediadruckwerk becomes early investor in Fujifilm's Jet Press 750S B2 inkjet press

Mediadruckwerk becomes early investor in Fujifilm's Jet Press 750S B2 inkjet...

15/11/2018

FloriColor: One of the first companies in Europe to invest in Fujifilm's new Jet Press 750S B2 inkjet press

FloriColor: One of the first companies in Europe to invest in Fujifilm's new...

15/11/2018

Fujifilm announces the fastest full colour, B2 sheet-fed digital press on the market: The Jet Press 750S

Fujifilm announces the fastest full colour, B2 sheet-fed digital press on the ma...

15/11/2018

Fujifilm announces XMF ColorPath Brand Color Optimizer

Fujifilm announces XMF ColorPath Brand Color Optimizer Brand new addition to Fujifilm's cloud-based XMF colour management suite allows the printing of brand...

15/11/2018

Comscore Receives Full UKOM Approval of Mobile Metrix Solution

Comscore Receives Full UKOM Approval of Mobile Metrix SolutionMobile Metrix ensures the complete and actionable measurement of the mobile ecosystem in the UK ...

15/11/2018

Sony releases 9 firmware update enhancing FTP file transfer functionality

Sony has released a firmware upgrade for its full-frame, mirrorless camera, the 9 (model ILCE-9) that allows photographers to transfer images to FTP servers du...

15/11/2018

NEW Machine Vision Phantom S210 and S200 Streaming Cameras

Introducing the newest member to the Phantom machine vision family: The Phantom S210 and S200, 2Gpx/sec (16 Gbps) machine vision cameras. The S210 reaches 1,73...

15/11/2018

Object Matrix Targets Modernization, Monetization of Sports-Content Workflows

Object Matrix Targets Modernization, Monetization of Sports-Content Workflows Cardiff, Wales, 15th November 2018 The Sports Video Group is pleased to welcome ...

15/11/2018

NTP Software is Refocused and is Now DefendX Software

Chelmsford, MA, USA - Tuesday, April 17, 2018...